Microemulsions as Potent Drug Delivery Systems

Microemulsions as Antidiabetic Drug Delivery Systems

Glibenclamide is practically insoluble in water and its gastrointestinal absorption is limited by its dissolution rate. Therefore, to enhance the drug dissolution and its hypoglycemic effects, the drug was formulated in different microemulsion systems and in vitro/in vivo evaluated. Microemulsion systems were prepared by Water titration method in which surfactants and cosurfactants (S/CoS) were...

Pluronic as nano-carier for drug delivery systems

A common approach for building a drug delivery system is to incorporate the drug within the nanocarrier that results in increased solubility, metabolic stability, and improved circulation time. However, recent developments indicate that selection of polymer nanomaterials can implement more than only inert carrier functions by being biological response modifiers. One representative of such mater...

Microemulsions as potential ocular drug delivery systems: phase diagrams and physical properties depending on ingredients.

The microemulsion systems, both o/w and w/o, composed of isopropyl myristate, soybean lecithin (Epikuron 200), Polysorbate 80, Cremophor EL, n-butanol and triacetine, taken at various amounts and in various combinations, were tested in order to assess their physical-chemical properties. Some ingredients of the microemulsions were physiologically acceptable, except one formulation containing n-b...

Microemulsions- Potential Carrier for Improved Drug Delivery

The novel carriers have been exploited through almost all the routes of administration. Association of drugs with carriers is normally noncovalent, based on collective strength of weak binding forces. Many newer carriers are evolving with the advent of technology and the demand of targeted delivery like microemulsions. Microemulsions are clear, stable, isotropic mixtures of oil, water and surfa...

Microemulsions: A potential novel drug delivery system